Table 3: IC50 values of the isolated complexes.
Compounds | No. | In vitro cytotoxicity IC50 (μg/mL) | |
Hela | MCF-7 | ||
[Co(tric-H)2]·0.5H2O | (1) | 11.94 | 7.34 |
[Co(tric)2Cl2]·2.5H2O | (2) | 41.39 | 44.23 |
[Cu(tric)2]Cl2·3H2O | (3) | 48.2 | 58.0 |
[Ni(tric)2Cl2(H2O)2]·H2O | (4) | 30.0 | 28.0 |
[Ni(tric-H)2(H2O)2] | (5) | 54.3 | 59.1 |
[Cd(tric)2(Ac)2]·H2O | (6) | 23.48 | 14.3 |
[Zn(tric)2Cl2]·EtOH | (7) | 33.5 | 37.7 |
5-Fluorouracil | 4.8 | 5.4 | |
IC50 (μg/mL): 1–10 (very strong), 11–20 (strong), 21–50 (moderate), 51–100 (weak), and above 100 (noncytotoxic). |